Research Associate in Ophthalmology
University of Pennsylvania

Philadelphia, Pennsylvania


Research Associate in Ophthalmology

Location:
Philadelphia, PA
Open Date:
Jul 9, 2021
Close Date:
Jul 9, 2023
Description:

The Department of Ophthalmology at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for a Research Associate position in the Academic Support Staff. This appointment will be initially for one (1) year and continuation during that time period and renewal are based on satisfactory performance and availability of funding (limited to three (3) years).

Responsibilities may include designing and conducting experiments, analyzing data, preparing and presenting research findings at meetings, helping to write scientific manuscripts, and applying for fellowships/grants.

The successful applicant will conduct research on the pathobiology and genetic risk factors of primary open-angle glaucoma (POAG), with an opportunity to participate in a large NIH-funded study uniquely focused on identifying phenotypic and genetic variants associated with POAG in African Americans.

Our group is interested in understanding the molecular processes that occur in the eye in course of glaucoma, which is the leading cause of irreversible blindness in the world. Establishing the function of genes associated with POAG is of great importance. We are interested in establishing gene function by generating in vitro and in vivo models to better understand mechanisms underlying retinal ganglion cell (RGC) degeneration in glaucoma. These will be used to develop novel therapeutic strategies.


Qualifications:

Applicants must have an Ph.D. and/or M.D. degree. Qualifications include less than three years of postdoctoral experience, and a strong publication record. Experience is required in the specific area of working with rodent models of glaucoma or retinal degeneration, electrophysiology, molecular and cellular neurobiology, gene editing with CRISPR/Cas9 and in vitro cell culture experiments including stem cell or iPSC derived culture. The position calls for a highly motivated candidate with a strong background in neurobiology, molecular biology and/or cellular biology. Good oral and written communication skills are required



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