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Job no: 939834
The overarching goal of the Center for Catalysis in Biomimetic Confinement (CCBC) is to understand the means by which nature spatially organizes catalysis across scales using compartmentalization in bacteria. The team of investigators from Michigan State University, Argonne National Laboratory and Lawrence Berkeley National Laboratory will work together to acquire a fundamental understanding of how multi-step reaction pathways are confined within and optimized by selectively permeable protein-based shells of Bacterial Microcompartments (BMCs). The CCBC will apply this knowledge to establish BMC shell proteins as building blocks that can be used for confined, hierarchically-ordered biological and synthetic multi-step catalysis for reactions with long-range goals that involve addressing global challenges related to energy and the environment. The Parent lab (https://kparentlab.natsci.msu.edu/) traditionally studies complex protein assemblies such as bacteriophage and giant viruses, and is applying their expertise in single particle cryo-EM to understand BMC shell assemblies.
Equal Employment Opportunity StatementAll qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, citizenship, age, disability or protected veteran status.
Required DegreeDoctorate -Biochemistry or related field
Minimum RequirementsDemonstration of a strong publication record and experience in working with proteins.
Desired QualificationsExperience with structural biology and computational expertise.
Review of Applications Begins On
04/16/2024
Websitewww.https://kparentlab.natsci.msu.edu/
Department StatementCryo-EM facilities available at MSU
Michigan State University houses a number of state of the art core facilities under the umbrella of the "Research Technology Support Facility" including a modern cryo-EM suite (https://cryo-em.natsci.msu.edu/about/index.aspx). This includes a Talos Arctica outfitted with an autoloader, Falcon4i direct detector and a Selectris energy filter. A Titan Krios G4 with cold FEG, Falcon 4i and SelectrisX energy filter equipped with a micro-ED package will be installed this summer. In addition, we will be installing a Helios Hydra FIB-SEM instrument this summer as well. Cryo-EM or other structural biology method experience is helpful, but not necessary. Training opportunities for all aspects of grid preparation, sample imaging, and post imaging analysis are available.
MSU StatementMichigan State University has been advancing the common good with uncommon will for more than 160 years. One of the top research universities in the world, MSU pushes the boundaries of discovery and forges enduring partnerships to solve the most pressing global challenges while providing life-changing opportunities to a diverse and inclusive academic community through more than 200 programs of study in 17 degree-granting colleges.
Advertised: Apr 5, 2024 Eastern Daylight Time
Applications close: Apr 5, 2026 Eastern Daylight Time
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